Pedunculopontine Gamma Band Activity and Development

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Pedunculopontine Gamma Band Activity and Development

This review highlights the most important discovery in the reticular activating system in the last 10 years, the manifestation of gamma band activity in cells of the reticular activating system (RAS), especially in the pedunculopontine nucleus, which is in charge of waking and rapid eye movement (REM) sleep. The identification of different cell groups manifesting P/Q-type Ca(2+) channels that c...

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Pedunculopontine Nucleus Gamma Band Activity-Preconscious Awareness, Waking, and REM Sleep

The pedunculopontine nucleus (PPN) is a major component of the reticular activating system (RAS) that regulates waking and REM sleep, states of high-frequency EEG activity. Recently, we described the presence of high threshold, voltage-dependent N- and P/Q-type calcium channels in RAS nuclei that subserve gamma band oscillations in the mesopontine PPN, intralaminar parafascicular nucleus (Pf), ...

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1 Gamma band unit activity and population responses 1 in the pedunculopontine nucleus ( PPN ) 2

27 The pedunculopontine nucleus (PPN) is involved in the activated states of waking and 28 paradoxical sleep, forming part of the reticular activating system (RAS). The studies described 29 tested the hypothesis that single unit and/or population responses of PPN neurons are capable 30 of generating gamma band frequency activity. Whole-cell patch clamp recordings (immersion 31 chamber) and popu...

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Gamma band unit activity and population responses in the pedunculopontine nucleus.

The pedunculopontine nucleus (PPN) is involved in the activated states of waking and paradoxical sleep, forming part of the reticular activating system (RAS). The studies described tested the hypothesis that single unit and/or population responses of PPN neurons are capable of generating gamma band frequency activity. Whole cell patch clamp recordings (immersion chamber) and population response...

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High-threshold Ca2+ channels behind gamma band activity in the pedunculopontine nucleus (PPN)

The pedunculopontine nucleus (PPN) is part of the Reticular Activating System, and active during waking and REM sleep. Previous results showed that all PPN cells plateau at gamma frequencies and intrinsic membrane oscillations in PPN neurons are mediated by high-threshold N- and P/Q-type Ca(2+) channels. The present study was designed to determine whether some PPN cells have only N-, only P/Q-,...

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ژورنال

عنوان ژورنال: Brain Sciences

سال: 2015

ISSN: 2076-3425

DOI: 10.3390/brainsci5040546